329045

4-Fluor-3-nitrobenzoesäure

98%

• Lineare Formel: FC₆H₃(NO₂)CO₂H
• CAS-Nummer: 453-71-4
• Molekulargewicht: 185.11
• EG-Nummer: 207-221-3
• MDL-Nummer: MFCD00007058
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24859766
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 98%
• Form: solid
• mp (Schmelzpunkt): 123-126 °C (lit.)
• Löslichkeit: 95% ethanol: soluble 50 mg/mL, clear, light yellow
• Funktionelle Gruppe: carboxylic acid; fluoro; nitro
• SMILES String: OC(=O)c1ccc(F)c(c1)[N+]([O-])=O
• InChI: 1S/C7H4FNO4/c8-5-2-1-4(7(10)11)3-6(5)9(12)13/h1-3H,(H,10,11)
• InChIKey: BOJWTAQWPVBIPG-UHFFFAOYSA-N

Beschreibung

Anwendung

4-Fluoro-3-nitrobenzoic acid was used:

• as starting reagent in the preparation of novel benzimidazoles having antimycobacterial activity
• in preparation of series of novel acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitors containing benzimidazole core structure
• in preparation of bis(heterocyclic) skeletal precursors for the Pictet-Spengler reaction
• in solid-phase synthesis of trisubstituted [1,3,5]triazino[1,2-a]benzimidazole-2,4(3H,10H)-diones

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves