230715

n-Butyllithium -Lösung

11.0 M in hexanes

• Synonym(e): n-BuLi, Butyllithium, Butyllithium -Lösung, Lithium-1-butanid
• Lineare Formel: CH₃(CH₂)₃Li
• CAS-Nummer: 109-72-8
• Molekulargewicht: 64.06
• Beilstein: 1209227
• MDL-Nummer: MFCD00009414
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24853833
• NACRES: NA.22

Eigenschaften

• Form: liquid
• Qualitätsniveau: 100
• Konzentration: 11.0 M in hexanes
• Dichte: 0.761 g/mL at 25 °C
• Lagertemp.: 2-8°C
• SMILES String: [Li]CCCC
• InChI: 1S/C4H9.Li/c1-3-4-2;/h1,3-4H2,2H3;
• InChIKey: MZRVEZGGRBJDDB-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

n-Butyllithium (n-BuLi) is an organolithium reagent commonly used as a strong base to form corresponding lithium salts by the deprotonation of nitrogen, oxygen, phosphorus, and carbon acids. Heterocyclic compounds, such as furans, thiophenes, oxazoles, pyrroles, etc, can be lithiated α to the ring heteroatom using n?BuLi. These lithiated salts reacting in situ with alkyl halides to obtain useful organic compounds by the formation of the C-C bond.

Anwendung

n-BuLi can be used as a reagent for lithium-halogen exchange reactions. Synthesis of various other useful reagents such as lithium diisopropylamide (LDA) and diphenylphosphine is prepared by in situ reaction with n-BuLi . In the polymerization of dienes, it can be employed as an initiator.

Verpackung

The 25 mL Sure/Seal^™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

Rechtliche Hinweise

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Sicherheitshinweise

• Piktogramme: GHS02,GHS05,GHS07,GHS08,GHS09
• Signalwort: Danger
• H-Sätze: H225 - H250 - H260 - H304 - H314 - H336 - H361f - H373 - H411
• P-Sätze: P210 - P231 + P232 - P280 - P301 + P310 + P331 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338 + P310 - P370 + P378
• Gefahreneinstufungen: Aquatic Chronic 2 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Pyr. Liq. 1 - Repr. 2 - Skin Corr. 1B - STOT RE 2 Inhalation - STOT SE 3 - Water-react 1
• Zielorgane: Central nervous system, Nervous system
• Zusätzliche Gefahrenhinweise: EUH014
• Lagerklassenschlüssel: 4.2 - Pyrophoric and self-heating hazardous materials
• WGK: WGK 2
• Flammpunkt (°F): -7.6 °F - closed cup
• Flammpunkt (°C): -22 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter