15502

1-Boc-piperazin

≥98.0% (GC)

• Synonym(e): Piperazin-1-carbonsäure-tert.-butylester
• Empirische Formel (Hill-System): C₉H₁₈N₂O₂
• CAS-Nummer: 57260-71-6
• Molekulargewicht: 186.25
• Beilstein: 879985
• MDL-Nummer: MFCD00075265
• UNSPSC-Code: 12352100
• eCl@ss: 32160406
• PubChem Substanz-ID: 57647377
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥98.0% (GC)
• Form: solid
• mp (Schmelzpunkt): 43-47 °C (lit.); 43-47 °C
• SMILES String: CC(C)(C)OC(=O)N1CCNCC1
• InChI: 1S/C9H18N2O2/c1-9(2,3)13-8(12)11-6-4-10-5-7-11/h10H,4-7H2,1-3H3
• InChIKey: CWXPZXBSDSIRCS-UHFFFAOYSA-N

Beschreibung

Anwendung

1-Boc-piperazine undergoes Buchwald-Hartwig amination with various aryl halides to form corresponding amine derivatives. It can be used to synthesize monosubstituted piperazine intermediates of many bioactive molecules and piperazine containing drug substances, such as trazodone.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): 235.4 °F - closed cup
• Flammpunkt (°C): 113 °C - closed cup
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves