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L4158

Sigma-Aldrich

Lithium acetate dihydrate

BioXtra

Synonym(s):

Acetic acid lithium salt

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About This Item

Linear Formula:
CH3COOLi · 2H2O
CAS Number:
6108-17-4
Molecular Weight:
102.02
Beilstein/REAXYS Number:
3564320
EC Number:
208-914-3
MDL number:
MFCD00066949
UNSPSC Code:
12352302
PubChem Substance ID:
24896363
NACRES:
NA.31

product line

BioXtra

Quality Level

200

form

solid

impurities

≤0.001% Phosphorus (P)
≤0.1% Insoluble matter

mp

53-56 °C (lit.)

solubility

H2O: 1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.5%
sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.001%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES string

[Li+].[H]O[H].[H]O[H].CC([O-])=O

InChI

1S/C2H4O2.Li.2H2O/c1-2(3)4;;;/h1H3,(H,3,4);;2*1H2/q;+1;;/p-1

InChI key

IAQLJCYTGRMXMA-UHFFFAOYSA-M

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General description

Lithium acetate dihydrate is one of the commercially available forms of lithium acetate. Lithium acetate is a common salt with variety of applications such as, product for efficient yeast transformation, drug formulation and therapy, lithium-6 CP/MAS standard, solvent and catalyst. In addition, it is also used as a buffer for gel electrophoresis of DNA and RNA, additive or catalyst for textiles and polymer production and as a precursor material for batteries and ferromagnetic nanoparticles.

Application

Lithium acetate dihydrate has been used for yeast transformation.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SLCK9680
SLCK2107
SLCJ9562
SLCH5780
SLCH1033

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Mating based split-ubiquitin assay for detection of protein interactions
Horaruang W and Zhang B
Bio-protocol, 7(4), e2258-e2258 (2017)
MtNODULE ROOT1 and MtNODULE ROOT2 are essential for indeterminate nodule identity
Magne K, et al.
Plant Physiology, 178(1), 295-316 (2018)
Single-step marker switching in Schizosaccharomyces pombe using a lithium acetate transformation protocol
Brown SD and Lorenz A
Bio-protocol, 6(24), 295-316 (2016)
Anhydrous lithium acetate polymorphs and its hydrates: three-dimensional coordination polymers
Martinez Casado FJ, et al.
Crystal Growth & Design, 11(4), 1021-1032 (2011)
Wenyi Hua et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 969, 117-122 (2014-08-30)
A highly sensitive, selective, and rugged quantification method was developed and validated for decitabine (5-aza-2'-deoxycytidine) in human plasma treated with 100μg/mL of tetrahydrouridine (THU). Chromatographic separation was accomplished using hydrophilic interaction liquid chromatography (HILIC) and detection used electrospray ionization (ESI)
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Articles

Introduction to Yeast Transformation

Transformation is the process by which exogenous DNA is introduced into a cell, resulting in a heritable change or genetic modification. This was first reported in Streptococcus pneumoniae by Griffith in 1928. Transforming principle of DNA was demonstrated by Avery et al. in 1944.

Protocols

Yeast Transformation Protocols

Yeasts are considered model systems for eukaryotic studies as they exhibit fast growth and have dispersed cells.

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