Skip to Content
MilliporeSigma

ZAK

Synonyms:
AZK, MLK7, MLT, MLTK, MRK, mlklak, pk
Species:
Human ZAK (51776), Mouse Zak (65964), Rat Zak (311743), chicken ZAK (424149), dog ZAK (478802), cow ZAK (519251)
UniProtKB ID:
Gene ID:
  • Human(51776) Summary: This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(65964) sterile alpha motif and leucine zipper containing kinase AZK
  • Rat(311743) sterile alpha motif and leucine zipper containing kinase AZK
  • chicken(424149) sterile alpha motif and leucine zipper containing kinase AZK
  • dog(478802) sterile alpha motif and leucine zipper containing kinase AZK
  • cow(519251) sterile alpha motif and leucine zipper containing kinase AZK

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
WH0051776M2
Monoclonal Anti-ZAK antibody produced in mouse, clone 3D11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
SAB1409434
Monoclonal Anti-ZAK antibody produced in mouse, clone 3B6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
SAB1409435
Monoclonal Anti-ZAK antibody produced in mouse, clone 2G7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot

Proteins

Product Number
Description
Species
SRP5101
ZAK, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human