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Merck

YWHAE

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide

Synonymes:
14-3-3E, KCIP-1, MDCR, MDS
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(7531) Summary: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(22627) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
  • Rat(29753) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
  • chicken(417554) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
  • domestic cat(101101425) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
  • dog(480645) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
  • naked mole-rat(101717238) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
  • domestic guinea pig(100714396) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
  • cow(282125) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
  • sheep(443300) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-YWHAE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-14-3-3 ε Antibody, CT, serum, Chemicon®,
Espèces réactives
bovine, chicken, human, mouse, rabbit, rat, sheep
Application
ELISA
immunohistochemistry

western blot
Anti-14-3-3 phospho Serine58 Antibody, Chemicon®, from rabbit,
Espèces réactives
human, rat
Application
western blot
Anti-14-3-3 epsilon Antibody, clone 4X6E1, Rabbit Monoclonal, ,
Espèces réactives
human, rat
Application
western blot
Anti-14-3-3 Antibody (pan), from rabbit, purified by affinity chromatography,
Espèces réactives
xenopus, bovine, chicken, fish, human, mouse, porcine, rabbit, rat, sheep, zebrafish
Application
immunohistochemistry
immunoprecipitation (IP)

western blot

Proteins

Référence du produit
Description
Espèce(s)
14-3-3 ε, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human
14-3-3 ε, untagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human YWHAE,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Ywhae,
Espèce(s)
mouse