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XRCC1

X-ray repair complementing defective repair in Chinese hamster cells 1

Synonyms:
RCC
Species:
Human XRCC1 (7515), Mouse Xrcc1 (22594), Rat Xrcc1 (84495), cow XRCC1 (616905), sheep XRCC1 (101106279), domestic guinea pig Xrcc1 (100727471), naked mole-rat Xrcc1 (101701146), fruit fly XRCC1 (31451), Zebrafish xrcc1 (445480), dog XRCC1 (476447) ...More
UniProtKB ID:
P18887, Q6IBS4, Q9HCB1
Gene ID:
  • Human(7515) Summary: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
  • Mouse(22594) X-ray repair complementing defective repair in Chinese hamster cells 1
  • Rat(84495) X-ray repair complementing defective repair in Chinese hamster cells 1
  • cow(616905) X-ray repair complementing defective repair in Chinese hamster cells 1
  • sheep(101106279) X-ray repair complementing defective repair in Chinese hamster cells 1
  • domestic guinea pig(100727471) X-ray repair complementing defective repair in Chinese hamster cells 1
  • naked mole-rat(101701146) X-ray repair complementing defective repair in Chinese hamster cells 1
  • fruit fly(31451) CG4208 gene product from transcript CG4208-RA
  • Zebrafish(445480) X-ray repair complementing defective repair in Chinese hamster cells 1
  • dog(476447) X-ray repair complementing defective repair in Chinese hamster cells 1
  • Horse(100070201) X-ray repair complementing defective repair in Chinese hamster cells 1
  • domestic cat(101091917) X-ray repair complementing defective repair in Chinese hamster cells 1

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
DR1103
Anti-XRCC1 Rabbit pAb, liquid, Calbiochem®,
Species Reactivity
human, mouse
Application
HPA006717
Anti-XRCC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
SAB5702395
Anti-XRCC1 Antibody, clone 2X1U4, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
MABE2020
Anti-XRCC1 Antibody, clone 33-2-5, ,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot
ABE559
Anti-Xrcc1 Antibody, serum, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunoprecipitation (IP)
western blot

esiRNA

Product Number
Description
Species
EHU903211
MISSION® esiRNA, targeting human XRCC1,
Species
human