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WNT1

wingless-type MMTV integration site family, member 1

Synonyms:
BMND16, INT1, OI15
Species:
UniProtKB ID:
Gene ID:
  • Human(7471) Summary: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008]
  • Mouse(22408) wingless-related MMTV integration site 1
  • Rat(24881) wingless-type MMTV integration site family, member 1
  • cow(540662) wingless-type MMTV integration site family, member 1
  • sheep(101103389) wingless-type MMTV integration site family, member 1
  • naked mole-rat(101722636) wingless-type MMTV integration site family, member 1
  • domestic guinea pig(100717026) wingless-type MMTV integration site family, member 1
  • Zebrafish(30128) wingless-type MMTV integration site family, member 1
  • dog(486560) wingless-type MMTV integration site family, member 1
  • Horse(100058859) wingless-type MMTV integration site family, member 1
  • domestic cat(101094190) wingless-type MMTV integration site family, member 1

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-WNT1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-WNT1 Antibody, clone 10C8, ascites fluid, clone 10C8, from mouse,
Species Reactivity
human, mouse
Application
flow cytometry
immunofluorescence

immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Wnt1,
Species
mouse