VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
Synonyms:
SYB2, VAMP-2
Species:
Human VAMP2 (6844), Mouse Vamp2 (22318), Rat Vamp2 (24803), domestic guinea pig Vamp2 (100732271), naked mole-rat Vamp2 (101711585), cow VAMP2 (282116), sheep VAMP2 (101122451), Zebrafish vamp2 (336281), dog VAMP2 (479491), domestic cat VAMP2 (101101516)
UniProtKB ID:
Gene ID:
- Human(6844) Summary: The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq, Jul 2008]
- Mouse(22318) vesicle-associated membrane protein 2
- Rat(24803) vesicle-associated membrane protein 2
- domestic guinea pig(100732271) vesicle-associated membrane protein 2 (synaptobrevin 2)
- naked mole-rat(101711585) vesicle-associated membrane protein 2 (synaptobrevin 2)
- cow(282116) vesicle-associated membrane protein 2 (synaptobrevin 2)
- sheep(101122451) vesicle-associated membrane protein 2 (synaptobrevin 2)
- Zebrafish(336281) vesicle-associated membrane protein 2
- dog(479491) vesicle-associated membrane protein 2 (synaptobrevin 2)
- domestic cat(101101516) vesicle-associated membrane protein 2 (synaptobrevin 2)
- chicken(424827) vesicle-associated membrane protein 2 (synaptobrevin 2)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Vesicle-Associated Membrane Protein 1/2 antibody produced in sheep, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot
western blot
Anti-Vesicle-Associated Membrane Protein 2 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
western blot