UHRF2
ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
Synonyms:
NIRF, RNF107, URF2
Species:
Human UHRF2 (115426), Mouse Uhrf2 (109113), Rat Uhrf2 (309331), chicken UHRF2 (431601), dog UHRF2 (474702), domestic cat UHRF2 (101093900), cow UHRF2 (613759), sheep UHRF2 (101117220), naked mole-rat Uhrf2 (101725090), domestic guinea pig Uhrf2 (100715709)
UniProtKB ID:
Gene ID:
- Human(115426) Summary: This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. [provided by RefSeq, Feb 2012]
- Mouse(109113) ubiquitin-like, containing PHD and RING finger domains 2
- Rat(309331) ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
- chicken(431601) ubiquitin-like, containing PHD and RING finger domains, 2
- dog(474702) ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
- domestic cat(101093900) ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
- cow(613759) ubiquitin-like with PHD and ring finger domains 2
- sheep(101117220) ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
- naked mole-rat(101725090) ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
- domestic guinea pig(100715709) ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-UHRF2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, rabbit
Application
immunohistochemistry
western blot
western blot
Anti-UHRF2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-UHRF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-UHRF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-E3 ubiquitin-protein ligase UHRF2 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot