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UBTF

upstream binding transcription factor, RNA polymerase I

Synonyms:
NOR-90, UBF, UBF-1, UBF1
Species:
Human UBTF (7343), Mouse Ubtf (21429), Rat Ubtf (25574), cow UBTF (497012), sheep UBTF (101114372), naked mole-rat Ubtf (101719434), domestic guinea pig Ubtf (100721775), Zebrafish ubtf (368509), Horse UBTF (100064724), chicken UBTF (100859792) ...More
UniProtKB ID:
P17480, A8K6R8
Gene ID:
  • Human(7343) Summary: This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011]
  • Mouse(21429) upstream binding transcription factor, RNA polymerase I
  • Rat(25574) upstream binding transcription factor, RNA polymerase I
  • cow(497012) upstream binding transcription factor, RNA polymerase I
  • sheep(101114372) upstream binding transcription factor, RNA polymerase I
  • naked mole-rat(101719434) upstream binding transcription factor, RNA polymerase I
  • domestic guinea pig(100721775) upstream binding transcription factor, RNA polymerase I
  • Zebrafish(368509) upstream binding transcription factor, RNA polymerase I
  • Horse(100064724) upstream binding transcription factor, RNA polymerase I
  • chicken(100859792) upstream binding transcription factor, RNA polymerase I
  • domestic cat(101099160) upstream binding transcription factor, RNA polymerase I
  • dog(480503) upstream binding transcription factor, RNA polymerase I

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB4504737
Anti-phospho-UBF (pSer484) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
SAB4503056
Anti-UBF1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
WH0007343M1
Monoclonal Anti-UBTF antibody produced in mouse, clone 6B6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
HPA006385
Anti-UBTF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
SAB1404509
Monoclonal Anti-UBTF antibody produced in mouse, clone 1A2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EHU085111
MISSION® esiRNA, targeting human UBTF,
Species
human
EMU061731
MISSION® esiRNA, targeting mouse Ubtf,
Species
mouse