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UBE2D2

ubiquitin-conjugating enzyme E2D 2

Synonyms:
E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH5B
Species:
Human UBE2D2 (7322), Rat Ube2d2 (641452), chicken UBE2D2 (416137), domestic cat UBE2D2 (101092081), dog UBE2D2 (612742), domestic guinea pig Ube2d2 (100732779), naked mole-rat Ube2d2 (101724153), cow UBE2D2 (541003)
UniProtKB ID:
P62837, D3DQC9, P51669, Q3MN78, Q96RP6
Gene ID:
  • Human(7322) Summary: Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
  • Rat(641452) ubiquitin-conjugating enzyme E2D 2
  • chicken(416137) ubiquitin-conjugating enzyme E2D 2
  • domestic cat(101092081) ubiquitin-conjugating enzyme E2D 2
  • dog(612742) ubiquitin-conjugating enzyme E2D 2
  • domestic guinea pig(100732779) ubiquitin-conjugating enzyme E2D 2
  • naked mole-rat(101724153) ubiquitin-conjugating enzyme E2D 2
  • cow(541003) ubiquitin-conjugating enzyme E2D 2

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Antibodies

Product Number
Description
Species Reactivity
Application
HPA003920
Anti-UBE2D2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
14-810
UbcH5b Conjugating Enzyme, 100 µg, The His6-tagged fusion protein of UbcH5b is charge & support ubiquitinylation in vitro. The His6-tagged UbcH5 family members all appear to form thiol ester conjugates with ubiquitin at a similar rate under similar conditions.,
Species
human

esiRNA

Product Number
Description
Species
EHU063521
MISSION® esiRNA, targeting human UBE2D2,
Species
human