TXNRD1
thioredoxin reductase 1
Synonyme:
GRIM-12, TR, TR1, TRXR1, TXNR
Spezies:
Human TXNRD1 (7296), Mouse Txnrd1 (50493), Rat Txnrd1 (58819), Zebrafish txnrd1 (352924), Horse TXNRD1 (100067923), chicken TXNRD1 (418082), dog TXNRD1 (474536), domestic cat TXNRD1 (101085222), cow TXNRD1 (282388), sheep TXNRD1 (101112970) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(7296) Summary: This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(50493) thioredoxin reductase 1
- Rat(58819) thioredoxin reductase 1
- Zebrafish(352924) thioredoxin reductase 1
- Horse(100067923) thioredoxin reductase 1
- chicken(418082) thioredoxin reductase 1
- dog(474536) thioredoxin reductase 1
- domestic cat(101085222) thioredoxin reductase 1
- cow(282388) thioredoxin reductase 1
- sheep(101112970) thioredoxin reductase 1
- naked mole-rat(101700382) thioredoxin reductase 1
- Domestic Rabbit(100356179) thioredoxin reductase 1
- domestic guinea pig(100718723) thioredoxin reductase 1
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Activity Assay
Produktnummer
Beschreibung
Spezies
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-TXNRD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
western blot
western blot
Anti-TXNRD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
western blot
Anti-TXNRD1 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot
Proteins
Produktnummer
Beschreibung
Spezies
Thioredoxin-Reduktase aus Rattenleber, buffered aqueous glycerol solution, ≥100 units/mg protein (Bradford),
Spezies
rat