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TRAF4

TNF receptor-associated factor 4

Synonyms:
CART1, MLN62, RNF83
Species:
UniProtKB ID:
Gene ID:
  • Human(9618) Summary: This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
  • Mouse(22032) TNF receptor associated factor 4
  • Rat(303285) Tnf receptor associated factor 4
  • naked mole-rat(101716536) TNF receptor-associated factor 4
  • domestic guinea pig(100723177) TNF receptor-associated factor 4
  • cow(781568) TNF receptor-associated factor 4
  • sheep(101107451) TNF receptor-associated factor 4
  • fruit fly(33638) TNF-receptor-associated factor 4
  • dog(100688511) TNF receptor-associated factor 4
  • Horse(100072085) TNF receptor-associated factor 4
  • domestic cat(101096365) TNF receptor-associated factor 4
  • chicken(417577) TNF receptor-associated factor 4

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TRAF4 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
proximity ligation assay

western blot
Anti-TRAF4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-TRAF4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-TRAF4 Antibody, clone 5MLN-2H1, ascites fluid, clone 5MLN-2H1, from mouse,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TRAF4,
Species
human
MISSION® esiRNA, targeting mouse Traf4,
Species
mouse