TNFRSF25
tumor necrosis factor receptor superfamily, member 25
Synonyms:
APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR
Species:
Human TNFRSF25 (8718), Mouse Tnfrsf25 (85030), Rat Tnfrsf25 (500592), cow TNFRSF25 (783432), sheep TNFRSF25 (101116668), domestic guinea pig Tnfrsf25 (100724303), naked mole-rat Tnfrsf25 (101703558), chicken TNFRSF25 (425564), dog TNFRSF25 (489632), domestic cat TNFRSF25 (101090784)
UniProtKB ID:
Gene ID:
- Human(8718) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation. [provided by RefSeq, Jul 2008]
- Mouse(85030) tumor necrosis factor receptor superfamily, member 25
- Rat(500592) tumor necrosis factor receptor superfamily, member 25
- cow(783432) tumor necrosis factor receptor superfamily, member 25
- sheep(101116668) tumor necrosis factor receptor superfamily, member 25
- domestic guinea pig(100724303) tumor necrosis factor receptor superfamily, member 25
- naked mole-rat(101703558) tumor necrosis factor receptor superfamily, member 25
- chicken(425564) tumor necrosis factor receptor superfamily, member 25
- dog(489632) tumor necrosis factor receptor superfamily, member 25
- domestic cat(101090784) tumor necrosis factor receptor superfamily, member 25
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TNFRSF25 antibody produced in mouse, clone 1H2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Monoclonal Anti-DR3 antibody produced in mouse, clone JD3,
Species Reactivity
human
Application
flow cytometry
esiRNA
Product Number
Description
Species