TLR9
toll-like receptor 9
Synonyms:
CD289
Species:
Human TLR9 (54106), Mouse Tlr9 (81897), Rat Tlr9 (338457), Zebrafish tlr9 (403128), domestic cat TLR9 (493839), Horse TLR9 (100009693), dog TLR9 (403502), cow TLR9 (282602), sheep TLR9 (494547), Goat TLR9 (100860819)
UniProtKB ID:
Gene ID:
- Human(54106) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Jul 2008]
- Mouse(81897) toll-like receptor 9
- Rat(338457) toll-like receptor 9
- Zebrafish(403128) toll-like receptor 9
- domestic cat(493839) toll-like receptor 9
- Horse(100009693) toll-like receptor 9
- dog(403502) toll-like receptor 9
- cow(282602) toll-like receptor 9
- sheep(494547) toll-like receptor 9
- Goat(100860819) toll-like receptor 9
- naked mole-rat(101715478) toll-like receptor 9
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Small Molecule - Antagonist
Product Number
Description
Species
2-[4-[(7-Chloro-4-quinolinyl)amino]pentyl] amino ethanol, British Pharmacopoeia (BP) Reference Standard,
Species
human
Hydroxychloroquine sulfate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
ANTI-TLR9 antibody produced in mouse, clone 2C3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
ANTI-TLR9 antibody produced in mouse, clone 1E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-TLR9, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, goat, horse, human, pig, sheep
Application
western blot
Anti-TLR9 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
ANTI-TLR9 antibody produced in mouse, clone 2G3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot