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Merck

TLR9

toll-like receptor 9

同義詞:
CD289
物種:
Human TLR9 (54106), Mouse Tlr9 (81897), Rat Tlr9 (338457), Zebrafish tlr9 (403128), domestic cat TLR9 (493839), Horse TLR9 (100009693), dog TLR9 (403502), cow TLR9 (282602), sheep TLR9 (494547), Goat TLR9 (100860819)
UniProtKB ID:
Q9NR96, B3Y661, D1CS56, Q6UVZ2, Q9HD68, Q9HD69, Q9HD70, Q9NYC2
基因 ID:
  • Human(54106) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Jul 2008]
  • Mouse(81897) toll-like receptor 9
  • Rat(338457) toll-like receptor 9
  • Zebrafish(403128) toll-like receptor 9
  • domestic cat(493839) toll-like receptor 9
  • Horse(100009693) toll-like receptor 9
  • dog(403502) toll-like receptor 9
  • cow(282602) toll-like receptor 9
  • sheep(494547) toll-like receptor 9
  • Goat(100860819) toll-like receptor 9
  • naked mole-rat(101715478) toll-like receptor 9

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Small Molecule - Antagonist

產品編號
描述
物種
H0915
羟氯喹 硫酸酯, ≥98% (HPLC), powder,
物種
human
1327000
硫酸羟氯喹, United States Pharmacopeia (USP) Reference Standard,
物種
human
TMT00427
2-((4-(7-Chloroquinolin-4-ylamino)pentyl)(ethyl)amino)ethanol, ,
物種
human
PHR1782
羟氯喹, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human
90527
硫酸羟氯喹, analytical standard,
物種
human

Antibodies

產品編號
描述
物種活性
應用
SAB3500313
Anti-TLR9 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物種活性
human, mouse
應用
ELISA
immunofluorescence
immunohistochemistry
western blot
WH0054106M3
Monoclonal Anti-TLR9 antibody produced in mouse, clone 1E8, purified immunoglobulin, buffered aqueous solution,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence
western blot
SAB2104136
Anti-TLR9, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, goat, horse, human, pig, sheep
應用
western blot
SAB1412155
ANTI-TLR9 antibody produced in mouse, clone 3B7, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
western blot