TLR3
toll-like receptor 3
Synonyms:
CD283, IIAE2
Species:
Human TLR3 (7098), Mouse Tlr3 (142980), Rat Tlr3 (364594), Zebrafish tlr3 (403126), Horse TLR3 (100009703), domestic cat TLR3 (493661), dog TLR3 (482905), chicken TLR3 (422720), cow TLR3 (281535), sheep TLR3 (554258) ...More
UniProtKB ID:
Gene ID:
- Human(7098) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. [provided by RefSeq, Jul 2008]
- Mouse(142980) toll-like receptor 3
- Rat(364594) toll-like receptor 3
- Zebrafish(403126) toll-like receptor 3
- Horse(100009703) toll-like receptor 3
- domestic cat(493661) toll-like receptor 3
- dog(482905) toll-like receptor 3
- chicken(422720) toll-like receptor 3
- cow(281535) toll-like receptor 3
- sheep(554258) toll-like receptor 3
- Domestic Rabbit(100009024) toll-like receptor 3
- naked mole-rat(101716400) toll-like receptor 3
- domestic guinea pig(100135634) toll-like receptor 3
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-TLR3 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot