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THRA

thyroid hormone receptor, alpha

Synonyms:
AR7, CHNG6, EAR7, ERB-T-1, ERBA, ERBA1, NR1A1, THRA1, THRA2, c-ERBA-1
Species:
Human THRA (7067), Mouse Thra (21833), Rat Thra (81812), chicken THRA (396251), domestic cat THRA (101095056), dog THRA (403601), cow THRA (532621), sheep THRA (443446), naked mole-rat Thra (101726699), Domestic Rabbit THRA (100303772)
UniProtKB ID:
P10827, A8K3B5, P21205, Q8N6A1, Q96H73
Gene ID:
  • Human(7067) Summary: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(21833) thyroid hormone receptor alpha
  • Rat(81812) thyroid hormone receptor alpha
  • chicken(396251) thyroid hormone receptor, alpha
  • domestic cat(101095056) thyroid hormone receptor, alpha
  • dog(403601) thyroid hormone receptor, alpha
  • cow(532621) thyroid hormone receptor, alpha
  • sheep(443446) thyroid hormone receptor, alpha
  • naked mole-rat(101726699) thyroid hormone receptor, alpha
  • Domestic Rabbit(100303772) thyroid hormone receptor, alpha
  • domestic guinea pig(100726737) thyroid hormone receptor, alpha

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Small Molecule - Agonist

Product Number
Description
Species
L0700000
Liothyronine sodium, European Pharmacopoeia (EP) Reference Standard,
Species
human
L0570000
Levothyroxine sodium, European Pharmacopoeia (EP) Reference Standard,
Species
human
1368008
Liothyronine, United States Pharmacopeia (USP) Reference Standard,
Species
human
1365000
Levothyroxine, United States Pharmacopeia (USP) Reference Standard,
Species
human
1365065
Levothyroxine sodium, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
T2877
3,3′,5-Triiodo-L-thyronine, ≥95% (HPLC), powder,
Species
rat, human
T7650
3,3′,5-Triiodothyroacetic acid, ≥90%,
Species
rat, human
T6397
3,3′,5-Triiodo-L-thyronine sodium salt, powder, BioReagent, suitable for cell culture,
Species
rat, human
T5516
3,3′,5-Triiodo-L-thyronine sodium salt, γ-irradiated, powder, suitable for, suitable for cell culture,
Species
rat, human
T1775
L-Thyroxine, powder, BioReagent, suitable for cell culture,
Species
human, mouse, rat

Antibodies

Product Number
Description
Species Reactivity
Application
SAB2501036
Anti-THRA antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, mouse, pig, rat
Application
ELISA
western blot
SAB2108789
Anti-THRA antibody produced in rabbit HRP conjugated, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat, zebrafish
Application
SAB2108787
Anti-THRA antibody produced in rabbit biotin conjugated, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat, zebrafish
Application
SAB4502968
Anti-Thyroid Hormone Receptor α, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
HPA009654
Anti-THRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

Product Number
Description
Species
T2877
3,3′,5-Triiodo-L-thyronine, ≥95% (HPLC), powder,
Species
rat, human
T6397
3,3′,5-Triiodo-L-thyronine sodium salt, powder, BioReagent, suitable for cell culture,
Species
rat, human
T5516
3,3′,5-Triiodo-L-thyronine sodium salt, γ-irradiated, powder, suitable for, suitable for cell culture,
Species
rat, human

Proteins

Product Number
Description
Species
SRP2046
Thyroid Hormone receptor,α1 human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Species
human
SRP2127
TR, α1, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
EMU069501
MISSION® esiRNA, targeting mouse Thra,
Species
mouse
EHU013761
MISSION® esiRNA, targeting human THRA,
Species
human