TDG
thymine-DNA glycosylase
Synonimy:
hTDG
Gatunek:
Human TDG (6996), Mouse Tdg (21665), Rat Tdg (114521), Zebrafish tdg (553789), dog TDG (475448), domestic cat TDG (101082502), Horse TDG (100053458), chicken TDG (395510), cow TDG (517825), sheep TDG (101123623) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(6996) Summary: The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]
- Mouse(21665) thymine DNA glycosylase
- Rat(114521) thymine-DNA glycosylase
- Zebrafish(553789) thymine-DNA glycosylase
- dog(475448) thymine-DNA glycosylase
- domestic cat(101082502) thymine-DNA glycosylase
- Horse(100053458) thymine-DNA glycosylase
- chicken(395510) thymine-DNA glycosylase
- cow(517825) thymine-DNA glycosylase
- sheep(101123623) thymine-DNA glycosylase
- naked mole-rat(101703457) thymine-DNA glycosylase
- domestic guinea pig(100724604) thymine-DNA glycosylase
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-TDG antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
western blot
Anti-TDG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
immunohistochemistry
Przeciwciało przeciw glikozylazie tyminy-DNA, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunocytochemistry
western blot
western blot