TDG
thymine-DNA glycosylase
Sinonimi:
hTDG
Specie:
Human TDG (6996), Mouse Tdg (21665), Rat Tdg (114521), Zebrafish tdg (553789), dog TDG (475448), domestic cat TDG (101082502), Horse TDG (100053458), chicken TDG (395510), cow TDG (517825), sheep TDG (101123623) ...Più
ID UniProtKB:
ID gene:
- Human(6996) Summary: The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]
- Mouse(21665) thymine DNA glycosylase
- Rat(114521) thymine-DNA glycosylase
- Zebrafish(553789) thymine-DNA glycosylase
- dog(475448) thymine-DNA glycosylase
- domestic cat(101082502) thymine-DNA glycosylase
- Horse(100053458) thymine-DNA glycosylase
- chicken(395510) thymine-DNA glycosylase
- cow(517825) thymine-DNA glycosylase
- sheep(101123623) thymine-DNA glycosylase
- naked mole-rat(101703457) thymine-DNA glycosylase
- domestic guinea pig(100724604) thymine-DNA glycosylase
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-TDG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Thymine-DNA Glycosylase Antibody, from rabbit, purified by affinity chromatography,
Reattività con
human, mouse
Applicazione
immunocytochemistry
western blot
western blot
Anti-TDG antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
western blot