TCEB1
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
Synonyms:
SIII, eloC
Species:
Human TCEB1 (6921), Mouse Tceb1 (67923), Rat Tceb1 (64525), chicken TCEB1 (420187), domestic cat TCEB1 (100628309), dog TCEB1 (477914), cow TCEB1 (540859), sheep TCEB1 (101107798), domestic guinea pig Tceb1 (100729701), naked mole-rat Tceb1 (101723674)
UniProtKB ID:
Gene ID:
- Human(6921) Summary: This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
- Mouse(67923) transcription elongation factor B (SIII), polypeptide 1
- Rat(64525) transcription elongation factor B (SIII), polypeptide 1
- chicken(420187) transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
- domestic cat(100628309) transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
- dog(477914) transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
- cow(540859) transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
- sheep(101107798) transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
- domestic guinea pig(100729701) transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
- naked mole-rat(101723674) transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ELOC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence