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Merck

TBX21

T-box 21

Synonymes:
T-PET, T-bet, TBET, TBLYM
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(30009) Summary: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq, Jul 2008]
  • Mouse(57765) T-box 21
  • Rat(303496) T-box 21
  • Zebrafish(797797) T-box 21
  • domestic cat(101097604) T-box 21
  • dog(491044) T-box 21
  • domestic guinea pig(100722972) T-box 21
  • naked mole-rat(101696563) T-box 21
  • cow(538933) T-box 21
  • sheep(101118711) T-box 21

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Antibodies

Référence du produit
Description
Espèces réactives
Application
T-bet (MRQ-46) Rabbit Monoclonal Antibody, ,
Espèces réactives
human
Application
immunohistochemistry
Anti-TBX21 Antibody, clone 1B21 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
affinity binding assay
flow cytometry

immunocytochemistry

western blot
Anti-TBX21 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, human, pig
Application
immunohistochemistry
western blot
Anti-TBX21 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Espèces réactives
human
Application
western blot
Monoclonal Anti-TBX21 antibody produced in mouse, clone 3D7, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human, mouse
Application
ELISA
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human TBX21,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Tbx21,
Espèce(s)
mouse