Skip to Content
MilliporeSigma

TANK

TRAF family member-associated NFKB activator

Synonyms:
I-TRAF, ITRAF, TRAF2
Species:
UniProtKB ID:
Gene ID:
  • Human(10010) Summary: The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
  • Mouse(21353) TRAF family member-associated Nf-kappa B activator
  • Rat(252961) TRAF family member-associated NFKB activator
  • cow(539513) TRAF family member-associated NFKB activator
  • sheep(101108632) TRAF family member-associated NFKB activator
  • naked mole-rat(101698139) TRAF family member-associated NFKB activator
  • Domestic Rabbit(100339142) TRAF family member-associated NFKB activator
  • domestic guinea pig(100721939) TRAF family member-associated NFKB activator
  • Zebrafish(767660) TRAF family member-associated NFKB activator
  • dog(608092) TRAF family member-associated NFKB activator
  • Horse(100068006) TRAF family member-associated NFKB activator
  • Horse(100051339) TRAF family member-associated NFKB activator
  • domestic cat(101094867) TRAF family member-associated NFKB activator
  • chicken(424190) TRAF family member-associated NFKB activator

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TANK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-TANK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-TANK (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunocytochemistry

western blot
Anti-TANK (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-TANK (AB2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Tank,
Species
mouse
MISSION® esiRNA, targeting human TANK,
Species
human