TAF1
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
Synonyms:
BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, N-TAF1, NSCL2, OF, P250, TAF2A, TAFII250, XDP
Species:
Human TAF1 (6872), Mouse Taf1 (270627), Rat Taf1 (317256), fruit fly Taf1 (40813), dog TAF1 (491950), Horse TAF1 (100056106), domestic cat TAF1 (101093583), Zebrafish taf1 (555452), chicken TAF1 (422204), domestic guinea pig Taf1 (100736214) ...More
UniProtKB ID:
Gene ID:
- Human(6872) Summary: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the rate of transcription initiation. This subunit contains two independent protein kinase domains at the N and C-terminals, but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme. This gene is part of a complex transcriptional unit (TAF1/DYT3), wherein some products share exons with TAF1 as well as additional exons downstream.[provided by RefSeq, Aug 2009]
- Mouse(270627) TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor
- Rat(317256) TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor
- fruit fly(40813) TBP-associated factor 1
- dog(491950) TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
- Horse(100056106) TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
- domestic cat(101093583) TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
- Zebrafish(555452) TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor
- chicken(422204) TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
- domestic guinea pig(100736214) TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
- Domestic Rabbit(100348935) TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
- naked mole-rat(101705178) TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
- cow(504792) TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
- cow(785085) TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
- sheep(101123273) TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-TAFII250 Antibody, clone 6B3, clone 6B3, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-TAF1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, human, pig, rabbit, rat
Application
ChIP
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TAF1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry
immunohistochemistry
Anti-TAF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-TAF1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, pig, rabbit, rat
Application
ChIP
western blot
western blot