SSH1
slingshot protein phosphatase 1
Synonyms:
SSH1L
Species:
Human SSH1 (54434), Mouse Ssh1 (231637), Rat Ssh1 (304580), chicken SSH1 (427699), chicken SSH1 (101668825), chicken SSH1 (101750781), domestic cat SSH1 (101094543), Horse SSH1 (100066801), dog SSH1 (477526), cow SSH1 (538233) ...More
UniProtKB ID:
Gene ID:
- Human(54434) Summary: The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
- Mouse(231637) slingshot homolog 1 (Drosophila)
- Rat(304580) slingshot protein phosphatase 1
- chicken(427699) slingshot homolog 1 (Drosophila)
- chicken(101668825) slingshot protein phosphatase 1
- chicken(101750781) slingshot protein phosphatase 1
- domestic cat(101094543) slingshot homolog 1 (Drosophila)
- Horse(100066801) slingshot homolog 1 (Drosophila)
- dog(477526) slingshot homolog 1 (Drosophila)
- cow(538233) slingshot protein phosphatase 1
- sheep(101116093) slingshot homolog 1 (Drosophila)
- naked mole-rat(101714823) slingshot protein phosphatase 1
- domestic guinea pig(100718532) slingshot protein phosphatase 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-SSH1 antibody produced in mouse, clone 2F9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-SSH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-SSH1 Antibody, clone 12C6.1, clone 12C6.1, from mouse,
Species Reactivity
human
Application
western blot