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SPTLC2

serine palmitoyltransferase, long chain base subunit 2

Synonyms:
HSN1C, LCB2, LCB2A, NSAN1C, SPT2, hLCB2a
Species:
UniProtKB ID:
Gene ID:
  • Human(9517) Summary: This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011]
  • Mouse(20773) serine palmitoyltransferase, long chain base subunit 2
  • Rat(366697) serine palmitoyltransferase, long chain base subunit 2
  • chicken(423379) serine palmitoyltransferase, long chain base subunit 2
  • dog(480403) serine palmitoyltransferase, long chain base subunit 2
  • Horse(100059392) serine palmitoyltransferase, long chain base subunit 2
  • domestic cat(101081055) serine palmitoyltransferase, long chain base subunit 2
  • domestic guinea pig(100719612) serine palmitoyltransferase, long chain base subunit 2
  • naked mole-rat(101702355) serine palmitoyltransferase, long chain base subunit 2
  • Domestic Rabbit(100358555) serine palmitoyltransferase, long chain base subunit 2
  • cow(537972) serine palmitoyltransferase, long chain base subunit 2
  • sheep(101115373) serine palmitoyltransferase, long chain base subunit 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SPTLC2 (C-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
western blot
Anti-SPTLC2 Antibody, serum, from rabbit,
Species Reactivity
xenopus, bovine, chicken, human, mouse, rat
Application
western blot
Anti-Sptlc2 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SPTLC2,
Species
human