SPO11
SPO11 meiotic protein covalently bound to DSB
Synonyms:
CT35, SPATA43, TOPVIA
Species:
Human SPO11 (23626), Mouse Spo11 (26972), Rat Spo11 (366261), Zebrafish spo11 (402982), chicken SPO11 (768915), domestic cat SPO11 (101090003), Horse SPO11 (100050365), dog SPO11 (610247), cow SPO11 (524105), sheep SPO11 (101118122) ...More
UniProtKB ID:
Gene ID:
- Human(23626) Summary: Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described. [provided by RefSeq, Jul 2008]
- Mouse(26972) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
- Rat(366261) SPO11 meiotic protein covalently bound to DSB
- Zebrafish(402982) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
- chicken(768915) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
- domestic cat(101090003) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
- Horse(100050365) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
- dog(610247) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
- cow(524105) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
- sheep(101118122) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
- Domestic Rabbit(100359270) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
- naked mole-rat(101706565) SPO11 meiotic protein covalently bound to DSB
- domestic guinea pig(100725083) SPO11 meiotic protein covalently bound to DSB
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SPO11 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-SPO11 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, human, rat
Application
western blot
Anti-SPO11 Antibody, clone 180, clone 180, from mouse,
Species Reactivity
mouse
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot