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Merck

SOD3

superoxide dismutase 3, extracellular

Synonyms:
EC-SOD
Species:
UniProtKB ID:
Gene ID:
  • Human(6649) Summary: This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM. [provided by RefSeq, Jul 2008]
  • Mouse(20657) superoxide dismutase 3, extracellular
  • Rat(25352) superoxide dismutase 3, extracellular
  • fruit fly(36232) Superoxide dismutase 3
  • chicken(422810) superoxide dismutase 3, extracellular
  • dog(488855) superoxide dismutase 3, extracellular
  • naked mole-rat(101703009) superoxide dismutase 3, extracellular
  • Domestic Rabbit(100009320) superoxide dismutase 3, extracellular
  • domestic guinea pig(100718762) superoxide dismutase 3, extracellular
  • cow(532481) superoxide dismutase 3, extracellular
  • Goat(100860810) superoxide dismutase 3, extracellular
  • sheep(101104150) superoxide dismutase 3, extracellular

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SOD3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Monoclonal Anti-SOD3 antibody produced in mouse, clone 4GG11G6, 1 mg/mL, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot

Proteins

Product Number
Description
Species
Superoxide Dismutase from human erythrocytes, essentially salt-free, lyophilized powder, ≥2,500 units/mg protein,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Sod3,
Species
mouse