SOCS3
suppressor of cytokine signaling 3
Synonyms:
ATOD4, CIS3, Cish3, SOCS-3, SSI-3, SSI3
Species:
Human SOCS3 (9021), Mouse Socs3 (12702), Rat Socs3 (89829), chicken SOCS3 (395299), Horse SOCS3 (100050730), domestic cat SOCS3 (101081846), dog SOCS3 (442949), cow SOCS3 (282081), sheep SOCS3 (100294595), domestic guinea pig Socs3 (100725088)
UniProtKB ID:
Gene ID:
- Human(9021) Summary: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008]
- Mouse(12702) suppressor of cytokine signaling 3
- Rat(89829) suppressor of cytokine signaling 3
- chicken(395299) suppressor of cytokine signaling 3
- Horse(100050730) suppressor of cytokine signaling 3
- domestic cat(101081846) suppressor of cytokine signaling 3
- dog(442949) suppressor of cytokine signaling 3
- cow(282081) suppressor of cytokine signaling 3
- sheep(100294595) suppressor of cytokine signaling 3
- domestic guinea pig(100725088) suppressor of cytokine signaling 3
- naked mole-rat(101704157) suppressor of cytokine signaling 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SOCS3 Antibody, clone 1B2, clone 1B2, Upstate®, from mouse,
Species Reactivity
human, mouse
Application
western blot
Anti-SOCS-3 Antibody, clone 2N6 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-SOCS3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Monoclonal Anti-SOCS3 antibody produced in mouse, clone 1E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunofluorescence
Monoclonal Anti-SOCS3 antibody produced in mouse, clone 2E5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA