SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
Synonyms:
ASM, ASMASE, NPD
Species:
Human SMPD1 (6609), Mouse Smpd1 (20597), Rat Smpd1 (308909), Zebrafish smpd1 (556700), chicken SMPD1 (419077), dog SMPD1 (485334), domestic cat SMPD1 (101099497), naked mole-rat Smpd1 (101699079), Domestic Rabbit SMPD1 (100353898), domestic guinea pig Smpd1 (100720041) ...More
UniProtKB ID:
Gene ID:
- Human(6609) Summary: The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010]
- Mouse(20597) sphingomyelin phosphodiesterase 1, acid lysosomal
- Rat(308909) sphingomyelin phosphodiesterase 1, acid lysosomal
- Zebrafish(556700) sphingomyelin phosphodiesterase 1, acid lysosomal
- chicken(419077) sphingomyelin phosphodiesterase 1, acid lysosomal
- dog(485334) sphingomyelin phosphodiesterase 1, acid lysosomal
- domestic cat(101099497) sphingomyelin phosphodiesterase 1, acid lysosomal
- naked mole-rat(101699079) sphingomyelin phosphodiesterase 1, acid lysosomal
- Domestic Rabbit(100353898) sphingomyelin phosphodiesterase 1, acid lysosomal
- domestic guinea pig(100720041) sphingomyelin phosphodiesterase 1, acid lysosomal
- cow(505097) sphingomyelin phosphodiesterase 1, acid lysosomal
- sheep(100307047) sphingomyelin phosphodiesterase 1, acid lysosomal
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SMPD1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, pig, rabbit, sheep
Application
western blot