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SLC10A2

solute carrier family 10 (sodium/bile acid cotransporter), member 2

Synonyms:
ASBT, IBAT, ISBT, NTCP2, PBAM
Species:
UniProtKB ID:
Gene ID:
  • Human(6555) Summary: This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Mar 2010]
  • Mouse(20494) solute carrier family 10, member 2
  • Rat(29500) solute carrier family 10 (sodium/bile acid cotransporter), member 2
  • Zebrafish(393329) solute carrier family 10 (sodium/bile acid cotransporter family), member 2
  • domestic cat(101083393) solute carrier family 10 (sodium/bile acid cotransporter family), member 2
  • dog(403448) solute carrier family 10 (sodium/bile acid cotransporter family), member 2
  • chicken(428018) solute carrier family 10 (sodium/bile acid cotransporter family), member 2
  • cow(525823) solute carrier family 10 (sodium/bile acid cotransporter family), member 2
  • sheep(101114965) solute carrier family 10 (sodium/bile acid cotransporter family), member 2
  • domestic guinea pig(100733636) solute carrier family 10 (sodium/bile acid cotransporter family), member 2
  • naked mole-rat(101696557) solute carrier family 10 (sodium/bile acid cotransporter family), member 2
  • Domestic Rabbit(100009550) solute carrier family 10 (sodium/bile acid cotransporter family), member 2

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SLC10A2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, horse, human, rat
Application
western blot
Anti-SLC10A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot