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SF3B3

splicing factor 3b, subunit 3, 130kDa

Synonyms:
RSE1, SAP130, SF3b130, STAF130
Species:
UniProtKB ID:
Gene ID:
  • Human(23450) Summary: This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq, Jul 2008]
  • Mouse(101943) splicing factor 3b, subunit 3
  • Rat(292019) splicing factor 3b, subunit 3
  • naked mole-rat(101723195) splicing factor 3b, subunit 3, 130kDa
  • domestic guinea pig(100723277) splicing factor 3b, subunit 3, 130kDa
  • cow(504962) splicing factor 3b, subunit 3, 130kDa
  • sheep(101113518) splicing factor 3b, subunit 3, 130kDa
  • Zebrafish(406824) splicing factor 3b, subunit 3
  • Horse(100054753) splicing factor 3b, subunit 3, 130kDa
  • domestic cat(101086362) splicing factor 3b, subunit 3, 130kDa
  • dog(479659) splicing factor 3b, subunit 3, 130kDa
  • chicken(415680) splicing factor 3b, subunit 3, 130kDa

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SAP130/SF3B3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
western blot
Anti-SF3B3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-SF3B3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-SF3B3/SAP130 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SF3B3 (1),
Species
human
MISSION® esiRNA, targeting mouse Sf3b3,
Species
mouse
MISSION® esiRNA, targeting human SF3B3 (2),
Species
human