SEP15
Synonyms:
Species:
Human SEP15 (9403), Mouse Sep15 (93684), Rat Sep15 (113922), Zebrafish sep15 (352923), Horse SEP15 (100052383), chicken SEP15 (424521), dog SEP15 (612493), domestic guinea pig Sep15 (100725885), Domestic Rabbit SEP15 (100338500), cow SEP15 (614360)
UniProtKB ID:
Gene ID:
- Human(9403) Summary: This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. This gene is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(93684) selenoprotein
- Rat(113922) selenoprotein 15
- Zebrafish(352923) selenoprotein 15
- Horse(100052383) 15 kDa selenoprotein
- chicken(424521) 15 kDa selenoprotein
- dog(612493) 15 kDa selenoprotein
- domestic guinea pig(100725885) selenoprotein
- Domestic Rabbit(100338500) 15 kDa selenoprotein
- cow(614360) 15 kDa selenoprotein
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