RYK
receptor-like tyrosine kinase
Synonyms:
D3S3195, JTK5, JTK5A, RYK1
Species:
Human RYK (6259), Mouse Ryk (20187), Rat Ryk (140585), Zebrafish ryk (558502), chicken RYK (395409), domestic cat RYK (101086838), dog RYK (477074), cow RYK (781353), sheep RYK (101114583), domestic guinea pig Ryk (100727608) ...More
UniProtKB ID:
Gene ID:
- Human(6259) Summary: The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012]
- Mouse(20187) receptor-like tyrosine kinase
- Rat(140585) receptor-like tyrosine kinase
- Zebrafish(558502) receptor-like tyrosine kinase
- chicken(395409) receptor-like tyrosine kinase
- domestic cat(101086838) receptor-like tyrosine kinase
- dog(477074) receptor-like tyrosine kinase
- cow(781353) receptor-like tyrosine kinase
- sheep(101114583) receptor-like tyrosine kinase
- domestic guinea pig(100727608) receptor-like tyrosine kinase
- naked mole-rat(101722098) receptor-like tyrosine kinase
- Domestic Rabbit(100008628) receptor-like tyrosine kinase
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ELISA
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-RYK antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-RYK (C-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-RYK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-RYK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry