RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
Synonyms:
AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Species:
Human RUNX1T1 (862), Mouse Runx1t1 (12395), Rat Runx1t1 (362489), Zebrafish runx1t1 (767809), Horse RUNX1T1 (100050630), domestic cat RUNX1T1 (101080942), chicken RUNX1T1 (395503), dog RUNX1T1 (487044), cow RUNX1T1 (538628), sheep RUNX1T1 (101113340) ...More
UniProtKB ID:
Gene ID:
- Human(862) Summary: This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
- Mouse(12395) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- Rat(362489) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- Zebrafish(767809) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- Horse(100050630) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- domestic cat(101080942) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- chicken(395503) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- dog(487044) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- cow(538628) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- sheep(101113340) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- naked mole-rat(101707177) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- domestic guinea pig(100724443) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-RUNX1T1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
proximity ligation assay
western blot
western blot
Anti-RUNX1T1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-RUNX1T1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, human, pig, rabbit
Application
immunohistochemistry
western blot
western blot
Anti-RUNX1T1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
esiRNA
Product Number
Description
Species