RRM1
ribonucleotide reductase M1
Synonyms:
R1, RIR1, RR1
Species:
Human RRM1 (6240), Mouse Rrm1 (20133), Rat Rrm1 (685579), Zebrafish rrm1 (30740), chicken RRM1 (419081), domestic cat RRM1 (101097343), Horse RRM1 (100053126), dog RRM1 (476823), Domestic Rabbit RRM1 (100345823), naked mole-rat Rrm1 (101708047) ...More
UniProtKB ID:
Gene ID:
- Human(6240) Summary: This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq, Jul 2008]
- Mouse(20133) ribonucleotide reductase M1
- Rat(685579) ribonucleotide reductase M1
- Zebrafish(30740) ribonucleotide reductase M1 polypeptide
- chicken(419081) ribonucleotide reductase M1
- domestic cat(101097343) ribonucleotide reductase M1
- Horse(100053126) ribonucleotide reductase M1
- dog(476823) ribonucleotide reductase M1
- Domestic Rabbit(100345823) ribonucleotide reductase M1
- naked mole-rat(101708047) ribonucleotide reductase M1
- domestic guinea pig(100728488) ribonucleotide reductase M1
- cow(505537) ribonucleotide reductase M1
- sheep(101116171) ribonucleotide reductase M1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-RRM1 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP167, affinity isolated antibody,
Species Reactivity
bovine, human, mouse
Application
flow cytometry
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Anti-RRM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-RRM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-RRM1 Antibody, clone 1E20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey
Application
affinity binding assay
flow cytometry
immunohistochemistry
western blot
flow cytometry
immunohistochemistry
western blot
Monoclonal Anti-RRM1 antibody produced in mouse, clone 1D6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species