跳轉至內容
Merck

RRM1

ribonucleotide reductase M1

同義詞:
R1, RIR1, RR1
物種:
UniProtKB ID:
基因 ID:
  • Human(6240) Summary: This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq, Jul 2008]
  • Mouse(20133) ribonucleotide reductase M1
  • Rat(685579) ribonucleotide reductase M1
  • Zebrafish(30740) ribonucleotide reductase M1 polypeptide
  • chicken(419081) ribonucleotide reductase M1
  • domestic cat(101097343) ribonucleotide reductase M1
  • Horse(100053126) ribonucleotide reductase M1
  • dog(476823) ribonucleotide reductase M1
  • Domestic Rabbit(100345823) ribonucleotide reductase M1
  • naked mole-rat(101708047) ribonucleotide reductase M1
  • domestic guinea pig(100728488) ribonucleotide reductase M1
  • cow(505537) ribonucleotide reductase M1
  • sheep(101116171) ribonucleotide reductase M1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

產品編號
描述
物種活性
應用
Anti-RRM1 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP167, affinity isolated antibody,
物種活性
bovine, human, mouse
應用
flow cytometry
immunofluorescence

immunohistochemistry

Small Molecule - Inhibitor

產品編號
描述
物種
羟基脲, United States Pharmacopeia (USP) Reference Standard,
物種
human
羟基脲, European Pharmacopoeia (EP) Reference Standard,
物種
human
羟基脲, 98%, powder,
物種
human
吉西他滨, ≥98% (HPLC),
物種
human
吉西他滨, United States Pharmacopeia (USP) Reference Standard,
物種
human