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Merck

RNF14

ring finger protein 14

Synonyms:
ARA54, HFB30, TRIAD2
Species:
UniProtKB ID:
Gene ID:
  • Human(9604) Summary: The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011]
  • Mouse(56736) ring finger protein 14
  • Rat(619577) ring finger protein 14
  • Zebrafish(415177) ring finger protein 14
  • chicken(416340) ring finger protein 14
  • domestic cat(101081275) ring finger protein 14
  • dog(478042) ring finger protein 14
  • Domestic Rabbit(100355608) ring finger protein 14
  • naked mole-rat(101714536) ring finger protein 14
  • domestic guinea pig(100725874) ring finger protein 14
  • cow(540274) ring finger protein 14
  • sheep(101108651) ring finger protein 14

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