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Merck

RLN1

relaxin 1

Synonyms:
H1, H1RLX, RLXH1, bA12D24.3.1, bA12D24.3.2
Species:
UniProtKB ID:
Gene ID:
  • Human(6013) Summary: Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. [provided by RefSeq, Jan 2013]
  • Mouse(19773) relaxin 1
  • Rat(25616) relaxin 1
  • Zebrafish(100996239) relaxin 1
  • dog(403742) relaxin 1
  • Domestic Rabbit(100009160) relaxin 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-RLN1, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-RLN1 antibody produced in mouse, clone 1H6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)

western blot

Proteins

Product Number
Description
Species
Relaxin-1 human, recombinant, expressed in E. coli, >95% (SDS-PAGE), lyophilized powder,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human RLN1,
Species
human
MISSION® esiRNA, targeting mouse Rln1,
Species
mouse