QPRT
quinolinate phosphoribosyltransferase
Synonyms:
QPRTase
Species:
Human QPRT (23475), Mouse Qprt (67375), Rat Qprt (293504), dog QPRT (607664), domestic cat QPRT (101087441), domestic guinea pig Qprt (100727900), naked mole-rat Qprt (101718250), cow QPRT (614254), Goat QPRT (100861315), sheep QPRT (101102696)
UniProtKB ID:
Gene ID:
- Human(23475) Summary: This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq, Jul 2008]
- Mouse(67375) quinolinate phosphoribosyltransferase
- Rat(293504) quinolinate phosphoribosyltransferase
- dog(607664) quinolinate phosphoribosyltransferase
- domestic cat(101087441) quinolinate phosphoribosyltransferase
- domestic guinea pig(100727900) quinolinate phosphoribosyltransferase
- naked mole-rat(101718250) quinolinate phosphoribosyltransferase
- cow(614254) quinolinate phosphoribosyltransferase
- Goat(100861315) quinolinate phosphoribosyltransferase
- sheep(101102696) quinolinate phosphoribosyltransferase
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-QPRT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
esiRNA
Product Number
Description
Species