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Merck

QDPR

quinoid dihydropteridine reductase

Synonyms:
DHPR, PKU2, SDR33C1
Species:
UniProtKB ID:
Gene ID:
  • Human(5860) Summary: This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase. [provided by RefSeq, Jul 2008]
  • Mouse(110391) quinoid dihydropteridine reductase
  • Rat(64192) quinoid dihydropteridine reductase
  • cow(618084) quinoid dihydropteridine reductase
  • sheep(101116833) quinoid dihydropteridine reductase
  • domestic guinea pig(100727648) quinoid dihydropteridine reductase
  • naked mole-rat(101712596) quinoid dihydropteridine reductase
  • chicken(426335) quinoid dihydropteridine reductase
  • domestic cat(101087576) quinoid dihydropteridine reductase
  • dog(479082) quinoid dihydropteridine reductase

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-QDPR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-QDPR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Monoclonal Anti-QDPR antibody produced in mouse, clone 2D4-1D3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Qdpr,
Species
mouse
MISSION® esiRNA, targeting human QDPR,
Species
human