PTPRM
protein tyrosine phosphatase, receptor type, M
Synonyms:
PTPRL1, R-PTP-MU, RPTPM, RPTPU, hR-PTPu
Species:
Human PTPRM (5797), Mouse Ptprm (19274), Rat Ptprm (29616), domestic guinea pig Ptprm (100714550), naked mole-rat Ptprm (101707728), Domestic Rabbit PTPRM (100356969), cow PTPRM (536092), sheep PTPRM (101102951), chicken PTPRM (426242), domestic cat PTPRM (101080832) ...More
UniProtKB ID:
Gene ID:
- Human(5797) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq, Jul 2008]
- Mouse(19274) protein tyrosine phosphatase, receptor type, M
- Rat(29616) protein tyrosine phosphatase, receptor type, M
- domestic guinea pig(100714550) protein tyrosine phosphatase, receptor type, M
- naked mole-rat(101707728) protein tyrosine phosphatase, receptor type, M
- Domestic Rabbit(100356969) protein tyrosine phosphatase, receptor type, M
- cow(536092) protein tyrosine phosphatase, receptor type, M
- sheep(101102951) protein tyrosine phosphatase, receptor type, M
- chicken(426242) protein tyrosine phosphatase, receptor type, M
- domestic cat(101080832) protein tyrosine phosphatase, receptor type, M
- Horse(100059664) protein tyrosine phosphatase, receptor type, M
- dog(480203) protein tyrosine phosphatase, receptor type, M
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PTPRM antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-Protein Tyrosine Phosphatase µ Antibody, clone SBK15, ascites fluid, clone SBK15, Chemicon®,
Species Reactivity
bovine, canine, human, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Proteins
Product Number
Description
Species