PTPN22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
Synonyms:
LYP, LYP1, LYP2, PEP, PTPN8
Species:
Human PTPN22 (26191), Mouse Ptpn22 (19260), Rat Ptpn22 (295338), cow PTPN22 (518992), sheep PTPN22 (101119860), naked mole-rat Ptpn22 (101711810), Domestic Rabbit PTPN22 (100354293), domestic guinea pig Ptpn22 (100717611), Zebrafish ptpn22 (565606), domestic cat PTPN22 (101099820) ...More
UniProtKB ID:
Gene ID:
- Human(26191) Summary: This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Mar 2009]
- Mouse(19260) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- Rat(295338) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- cow(518992) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- sheep(101119860) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- naked mole-rat(101711810) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- Domestic Rabbit(100354293) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- domestic guinea pig(100717611) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- Zebrafish(565606) protein tyrosine phosphatase, non-receptor type 22
- domestic cat(101099820) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- dog(483124) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- chicken(772032) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PTPN22 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab2,
Species Reactivity
human
Application
immunohistochemistry
Anti-PTPN22 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
Species Reactivity
human
Application
immunohistochemistry
Anti-PTPN22 Antibody, clone 3B3.1, culture supernatant, clone 3B3.1, from mouse,
Species Reactivity
human
Application
western blot
Monoclonal Anti-PTPN22 antibody produced in mouse, clone 1A6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Monoclonal Anti-PTPN22 antibody produced in mouse, clone 4F6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot