PTPN21
protein tyrosine phosphatase, non-receptor type 21
Synonyms:
PTPD1, PTPRL10
Species:
Human PTPN21 (11099), Mouse Ptpn21 (24000), Rat Ptpn21 (171070), Zebrafish ptpn21 (799627), domestic cat PTPN21 (101084369), Horse PTPN21 (100062018), dog PTPN21 (490823), chicken PTPN21 (423398), domestic guinea pig Ptpn21 (100723000), naked mole-rat Ptpn21 (101720006) ...More
UniProtKB ID:
Gene ID:
- Human(11099) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq, Jul 2008]
- Mouse(24000) protein tyrosine phosphatase, non-receptor type 21
- Rat(171070) protein tyrosine phosphatase, non-receptor type 21
- Zebrafish(799627) protein tyrosine phosphatase, non-receptor type 21
- domestic cat(101084369) protein tyrosine phosphatase, non-receptor type 21
- Horse(100062018) protein tyrosine phosphatase, non-receptor type 21
- dog(490823) protein tyrosine phosphatase, non-receptor type 21
- chicken(423398) protein tyrosine phosphatase, non-receptor type 21
- domestic guinea pig(100723000) protein tyrosine phosphatase, non-receptor type 21
- naked mole-rat(101720006) protein tyrosine phosphatase, non-receptor type 21
- cow(520178) protein tyrosine phosphatase, non-receptor type 21
- sheep(101113938) protein tyrosine phosphatase, non-receptor type 21
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Antibodies
Product Number
Description
Species Reactivity
Application
ANTI-PTPD1 (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-PTPN21 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-PTPN21 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-PTPN21 Antibody, clone 2K11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
esiRNA
Product Number
Description
Species