PTPN2
protein tyrosine phosphatase, non-receptor type 2
Synonyms:
PTN2, PTPT, TC-PTP, TCELLPTP, TCPTP
Species:
Human PTPN2 (5771), Mouse Ptpn2 (19255), Rat Ptpn2 (117063), chicken PTPN2 (396409), domestic cat PTPN2 (101095923), dog PTPN2 (490563), cow PTPN2 (540888), sheep PTPN2 (101106987), Domestic Rabbit PTPN2 (100338151), naked mole-rat Ptpn2 (101725549)
UniProtKB ID:
Gene ID:
- Human(5771) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011]
- Mouse(19255) protein tyrosine phosphatase, non-receptor type 2
- Rat(117063) protein tyrosine phosphatase, non-receptor type 2
- chicken(396409) protein tyrosine phosphatase, non-receptor type 2
- domestic cat(101095923) protein tyrosine phosphatase, non-receptor type 2
- dog(490563) protein tyrosine phosphatase, non-receptor type 2
- cow(540888) protein tyrosine phosphatase, non-receptor type 2
- sheep(101106987) protein tyrosine phosphatase, non-receptor type 2
- Domestic Rabbit(100338151) protein tyrosine phosphatase, non-receptor type 2
- naked mole-rat(101725549) protein tyrosine phosphatase, non-receptor type 2
- domestic guinea pig(100732081) protein tyrosine phosphatase, non-receptor type 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PTPN2 antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-PTPN2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-PTPN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PTPN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TC PTPase (PTPN2) Antibody, clone 9E9.1, clone 9E9.1, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Proteins
Product Number
Description
Species
TCPTP Protein, 10 µg, Un-tagged, recombinant, human TCPTP, amino acids 1-341. For use in Phosphatase Assays.,
Species
human
PTPN2, active, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
esiRNA
Product Number
Description
Species