PTCH1
patched 1
Synonyms:
BCNS, HPE7, NBCCS, PTC, PTC1, PTCH, PTCH11
Species:
Human PTCH1 (5727), Mouse Ptch1 (19206), Rat Ptch1 (89830), cow PTCH1 (520994), sheep PTCH1 (101112193), domestic guinea pig Ptch1 (100729719), naked mole-rat Ptch1 (101711146), Domestic Rabbit PTCH1 (100345046), Zebrafish ptch1 (30189), Horse PTCH1 (100033936) ...More
UniProtKB ID:
Gene ID:
- Human(5727) Summary: This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq, Jul 2008]
- Mouse(19206) patched homolog 1
- Rat(89830) patched 1
- cow(520994) patched 1
- sheep(101112193) patched 1
- domestic guinea pig(100729719) patched 1
- naked mole-rat(101711146) patched 1
- Domestic Rabbit(100345046) patched 1
- Zebrafish(30189) patched 1
- Horse(100033936) patched 1
- domestic cat(101085077) patched 1
- dog(484137) patched 1
- chicken(395806) patched 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PTCH1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-PTCH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-PATCHED, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-PTCH antibody produced in mouse, clone 8E1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-Protein patched homolog 1 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
western blot