Skip to Content
MilliporeSigma

PSMB10

proteasome (prosome, macropain) subunit, beta type, 10

Synonyms:
LMP10, MECL1, beta2i
Species:
UniProtKB ID:
Gene ID:
  • Human(5699) Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq, Jul 2008]
  • Mouse(19171) proteasome (prosome, macropain) subunit, beta type 10
  • Rat(291983) proteasome (prosome, macropain) subunit, beta type 10
  • domestic guinea pig(100730197) proteasome (prosome, macropain) subunit, beta type, 10
  • naked mole-rat(101701334) proteasome (prosome, macropain) subunit, beta type, 10
  • cow(282328) proteasome (prosome, macropain) subunit, beta type, 10
  • sheep(101116929) proteasome (prosome, macropain) subunit, beta type, 10
  • Zebrafish(64280) proteasome (prosome, macropain) subunit, beta type, 10
  • domestic cat(101082199) proteasome (prosome, macropain) subunit, beta type, 10
  • dog(489749) proteasome (prosome, macropain) subunit, beta type, 10

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PSMB10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-PSMB10 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, human, mouse, pig, rat
Application
western blot
Anti-PSMB10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Psmb10,
Species
mouse