PRCP
prolylcarboxypeptidase (angiotensinase C)
Synonyms:
HUMPCP, PCP
Species:
Human PRCP (5547), Mouse Prcp (72461), Rat Prcp (293118), Zebrafish prcp (436967), chicken PRCP (428096), Horse PRCP (100061830), domestic cat PRCP (101100665), dog PRCP (476788), domestic guinea pig Prcp (100734342), naked mole-rat Prcp (101719590) ...More
UniProtKB ID:
Gene ID:
- Human(5547) Summary: The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- Mouse(72461) prolylcarboxypeptidase (angiotensinase C)
- Rat(293118) prolylcarboxypeptidase (angiotensinase C)
- Zebrafish(436967) prolylcarboxypeptidase (angiotensinase C)
- chicken(428096) prolylcarboxypeptidase (angiotensinase C)
- Horse(100061830) prolylcarboxypeptidase (angiotensinase C)
- domestic cat(101100665) prolylcarboxypeptidase (angiotensinase C)
- dog(476788) prolylcarboxypeptidase (angiotensinase C)
- domestic guinea pig(100734342) prolylcarboxypeptidase (angiotensinase C)
- naked mole-rat(101719590) prolylcarboxypeptidase (angiotensinase C)
- cow(534927) prolylcarboxypeptidase (angiotensinase C)
- sheep(101107644) prolylcarboxypeptidase (angiotensinase C)
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PRCP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-PRCP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Proteins
Product Number
Description
Species
PrCP active human, recombinant, expressed in FreeStyle™ 293-F cells, ≥15% (SDS-PAGE),
Species
human