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Merck

PPP1R12B

protein phosphatase 1, regulatory subunit 12B

Synonymes:
MYPT2, PP1bp55
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4660) Summary: Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome. [provided by RefSeq, Oct 2011]
  • Mouse(329251) protein phosphatase 1, regulatory (inhibitor) subunit 12B
  • Rat(304813) protein phosphatase 1, regulatory subunit 12B
  • cow(100337338) protein phosphatase 1, regulatory subunit 12B
  • sheep(101110859) protein phosphatase 1, regulatory subunit 12B
  • Domestic Rabbit(100356902) protein phosphatase 1, regulatory subunit 12B
  • naked mole-rat(101711489) protein phosphatase 1, regulatory subunit 12B
  • domestic guinea pig(100729743) protein phosphatase 1, regulatory subunit 12B
  • chicken(395478) protein phosphatase 1, regulatory subunit 12B
  • Horse(100063928) protein phosphatase 1, regulatory subunit 12B
  • domestic cat(101098766) protein phosphatase 1, regulatory subunit 12B
  • dog(490230) protein phosphatase 1, regulatory subunit 12B

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-PPP1R12B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-PPP1R12B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Anti-PPP1R12B antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-PPP1R12B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-Phospho-PPP1R12A/PPP1R12B/PPP1R12C-T696 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse PPP1R12B,
Espèce(s)
mouse
MISSION® esiRNA, targeting human PPP1R12B (2),
Espèce(s)
human
MISSION® esiRNA, targeting human PPP1R12B (1),
Espèce(s)
human