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PPFIBP1

PTPRF interacting protein, binding protein 1 (liprin beta 1)

Synonyms:
L2, SGT2, hSGT2, hSgt2p
Species:
UniProtKB ID:
Gene ID:
  • Human(8496) Summary: The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(67533) PTPRF interacting protein, binding protein 1 (liprin beta 1)
  • Rat(312855) PTPRF interacting protein, binding protein 1 (liprin beta 1)
  • naked mole-rat(101715740) PTPRF interacting protein, binding protein 1 (liprin beta 1)
  • Domestic Rabbit(100342629) PTPRF interacting protein, binding protein 1 (liprin beta 1)
  • domestic guinea pig(100734144) PTPRF interacting protein, binding protein 1 (liprin beta 1)
  • cow(407130) PTPRF interacting protein, binding protein 1 (liprin beta 1)
  • sheep(101110491) PTPRF interacting protein, binding protein 1 (liprin beta 1)
  • Zebrafish(100329686) PTPRF interacting protein, binding protein 1 (liprin beta 1)
  • dog(486623) PTPRF interacting protein, binding protein 1 (liprin beta 1)
  • Horse(100064684) PTPRF interacting protein, binding protein 1 (liprin beta 1)
  • domestic cat(101082578) PTPRF interacting protein, binding protein 1 (liprin beta 1)
  • chicken(418219) PTPRF interacting protein, binding protein 1 (liprin beta 1)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PPFIBP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-Ppfibp1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ppfibp1,
Species
mouse