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MilliporeSigma

POLK

polymerase (DNA directed) kappa

Synonyms:
DINB1, DINP, POLQ
Species:
UniProtKB ID:
Gene ID:
  • Human(51426) Summary: External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007 [PubMed 17317631]
  • Mouse(27015) polymerase (DNA directed), kappa
  • Rat(171525) polymerase (DNA directed) kappa
  • naked mole-rat(101718580) polymerase (DNA directed) kappa
  • Domestic Rabbit(100352218) polymerase (DNA directed) kappa
  • domestic guinea pig(100726233) polymerase (DNA directed) kappa
  • cow(541218) polymerase (DNA directed) kappa
  • sheep(101109360) polymerase (DNA directed) kappa
  • Zebrafish(562749) polymerase (DNA directed) kappa
  • chicken(374003) polymerase (DNA directed) kappa
  • dog(479180) polymerase (DNA directed) kappa
  • domestic cat(101099613) polymerase (DNA directed) kappa
  • Horse(100065534) polymerase (DNA directed) kappa

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-POLK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-POLK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-POLK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-POLK antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, horse, human, mouse, pig, rat
Application
western blot
Monoclonal Anti-POLK antibody produced in mouse, clone 6F2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Polk,
Species
mouse
MISSION® esiRNA, targeting human POLK,
Species
human