PKM
pyruvate kinase, muscle
Synonyms:
CTHBP, OIP3, PK3, PKM2, TCB, THBP1
Species:
Human PKM (5315), Mouse Pkm (18746), Rat Pkm (25630), cow PKM (512571), sheep PKM (101109180), Domestic Rabbit PKM (100008676), naked mole-rat Pkm (101721034), domestic guinea pig Pkm (100736056), Horse PKM (100063687), domestic cat PKM (101092521)
UniProtKB ID:
Gene ID:
- Human(5315) Summary: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]
- Mouse(18746) pyruvate kinase, muscle
- Rat(25630) pyruvate kinase, muscle
- cow(512571) pyruvate kinase, muscle
- sheep(101109180) pyruvate kinase, muscle
- Domestic Rabbit(100008676) pyruvate kinase, muscle
- naked mole-rat(101721034) pyruvate kinase, muscle
- domestic guinea pig(100736056) pyruvate kinase, muscle
- Horse(100063687) pyruvate kinase, muscle
- domestic cat(101092521) pyruvate kinase, muscle
- dog(403874) pyruvate kinase, muscle
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PKM1 Antibody, serum, from rabbit,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
western blot
Anti-PKM2 Antibody, serum, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
ANTI-PKM1 (C-TERM L398) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
western blot
Anti-PKM1 Antibody, clone 1B15 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse
Application
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Phospho-PKM-Y105 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Proteins
Product Number
Description
Species
esiRNA
Product Number
Description
Species